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Pre-Treatment Preparation and Requirements

Understanding Your First SPRAVATO® Treatment at NuLife Health

Before your scheduled appointment, you’ll need to arrange appropriate transportation, as driving is prohibited for the remainder of the day following SPRAVATO® administration. Patients should plan ahead for transportation after treatment and should not drive or operate machinery until it is safe to do so. We recommend eating a light meal approximately two hours before your appointment, as some patients experience mild nausea during treatment. Avoid food and liquids for at least 60 minutes before treatment to help reduce the risk of nausea and discomfort.

Your medical team will have already reviewed your comprehensive health history, current medications, and treatment goals during your initial consultation. However, please inform us immediately if anything has changed regarding your health status, medications, or if you’ve experienced any concerning symptoms since your last visit. This ongoing communication helps us maintain the clinical excellence we’re known for, ensuring your treatment plan remains optimized for your specific needs. Bring any prescribed medications you typically take, comfortable clothing, and perhaps some calming music or reading material for the observation period.

The Treatment Process Step by Step

Upon arrival, our clinical staff will check your vital signs, including blood pressure and heart rate, establishing baseline measurements for comparison throughout your session. You’ll be escorted to a comfortable treatment room designed to promote relaxation and healing. The actual administration process involves using the SPRAVATO® nasal spray device under direct medical supervision. Depending on the appropriate dose, patients can expect to use 2 or 3 devices on a treatment day. Additionally, we will provide patients with an eye mask, noise-cancelling headphones, and a comfortable plush blanket for patients to relax after medication administration.

Our trained healthcare provider will demonstrate proper administration technique, ensuring you understand how to position the device and coordinate breathing for optimal absorption. Between each spray, you’ll wait five minutes, allowing the medication to be properly absorbed through the nasal mucosa. The entire administration process typically takes about 10 to 15 minutes, though we never rush patients who need additional time or support. Throughout this process, our staff remains present, monitoring your response and providing reassurance as needed.

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During Treatment Sensations and Experiences

  • Dissociative effects: Many patients report feeling disconnected from their surroundings or experiencing altered perceptions of time and space
  • Sensory changes: Colors may appear more vivid, sounds might seem distant or enhanced, and physical sensations can feel different than usual
  • Emotional shifts: Some experience emotional release, increased introspection, or temporary mood elevation during the session

These effects typically begin within 15 to 30 minutes after administration and generally peak around 40 minutes. Our experienced staff understands these are normal responses to SPRAVATO® and will help you navigate any unexpected sensations. We maintain a calm, supportive atmosphere throughout, adjusting lighting and environmental factors to enhance your comfort. Some patients find the experience profound and therapeutic, while others describe it as simply relaxing or mildly unusual.

Post-Treatment Monitoring and Recovery

Following administration, you’ll remain in our facility for a mandatory two-hour observation period. During this time, you’ll rest comfortably while our staff performs periodic checks, measuring blood pressure and assessing your overall wellbeing. Most dissociative effects substantially diminish within the first hour, though some patients report feeling slightly different for several hours afterward.

We encourage patients to use this recovery time for gentle reflection or rest. Many find journaling helpful for processing their experience, and we can provide materials if desired. Our staff remains available to discuss any concerns or observations you’d like to share, as these insights often prove valuable for optimizing future sessions and supporting your ongoing mental health journey.

Disclaimer

Our clinic is a certified Spravato REMS Treatment Center. Because Spravato can cause serious side effects, it is only available through a restricted program that requires administration under direct supervision in our clinic. Patients are monitored on-site for at least 2 hours following each treatment.

Understanding Ketamine Therapy
Frequently Asked Questions

There’s a good chance you’ve heard of ketamine as a recreational substance, but its medicinal value far outweighs its party persona. For decades, ketamine has been a FDA-approved anesthetic. But it has also been proven to effectively treat symptoms of anxiety and depression.

Ketamine is administered under the guidance of certified medical professionals. Physicians in operating rooms actually tend to favor ketamine over other anesthetics because of its low side effect profile—which is especially necessary for patients with low blood pressure and respiratory issues. Your IV ketamine treatment will be administered at an even lower dose than what is used as an anesthetic in operating rooms. Our clinic adheres to the dosing regimen and closely monitors patients in a controlled setting.

Most insurance companies cover SPRAVATO® for treatment-resistant depression so contact us to see if you are covered. Please contact us for questions about IV ketamine pricing.

SPRAVATO® nasal esketamine spray is covered by most insurance plans for treatment-resistant depression. Most insurance companies do not currently cover IV ketamine for depression. We are hopeful that this will change as more published research continues to prove the efficacy of this treatment.

Call us or schedule a free consult now to find out if you are covered. We’ll do all the work to figure out if you are covered.

Yes! How you choose to care for yourself is completely up to you, but we highly encourage people to continue seeing a talk therapist or psychiatrist once they’ve started ketamine treatment. Working with a talk therapist may help you to unpack any breakthroughs you experience during a ketamine journey.

Our team prefers to receive referrals before beginning treatment, but they are not required. We find that we are able to help people achieve the best results when we are able to work with a mental health provider to better understand your history, and develop a post-treatment plan. If you are not currently seeing a psychotherapist or psychiatrist, our physicians will perform a medical and psychiatric history screening. Additionally, we can assist you with a referral to work with a ketamine-assisted psychotherapist in our expansive network.

Contact us now to schedule a free consultation. We always develop an individualized treatment plan for each patient. We can provide patients a scheduling link for treatments once we have developed a treatment plan.

During your initial consultation, we will review your medical history and symptoms to determine if ketamine is right for you. Absolute contraindications to ketamine treatment include hypersensitivity/severe allergy to ketamine, active psychosis/mania, severe coronary artery disease, pregnancy and breastfeeding, uncontrolled hypertension, recent myocardial infarction, and intracranial aneurysms. Unfortunately, we also do not treat pediatric patients under the age of 18 at this time.

The following are relative contraindications that will be weighed on a case-by-case basis:

  • Obstructive sleep apnea
  • Respiratory issues due to weight
  • Medication risks (benzodiazepines, opioids)
  • Personality disorders
  • Acute suicidal ideation
  • Past substance/alcohol use disorder
  • Mild to moderate hypertension
  • History of epilepsy
  • Liver disease

There may be other conditions or reasons that patients might not be candidates for ketamine treatment.

Side effects from IV ketamine treatments are rare, and we conduct thorough medical pre-screenings to mitigate any chances of you feeling discomfort post-treatment. But every body is different. While most people walk away from ketamine treatment feeling relaxed and comfortable, some do report feelings of dizziness, elevated heart rate, nausea, hallucinations, and increased blood pressure. During treatment our certified physicians are always close by to monitor—don’t hesitate to let them know if you have any issues.

Ketamine is regulated by the FDA and legal for medical use in the United States when administered by certified medical providers.

Ketamine challenges the breakdown in the brain’s information synthesis capability by resetting brain structures and creating new neural connections. Patients can often achieve positive effects within hours to days from ketamine treatment. Traditional antidepressant medications usually require weeks of treatment prior to seeing effects.

We always recommend discussing dosage changes or continuation with your psychiatrist. You may continue taking antidepressants once you’ve begun ketamine treatment, as ketamine does not interact with the majority of antidepressant medications. Many people actually are able to lower their antidepressant dosage following ketamine therapy.

What Our Patients Say
Experiences from people who've walked this path before you

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